Cayman Public Holidays 2021
| NO | Date | Day | Holiday |
| 1 | 01 Jan 2021 | Friday | New Year's Day |
| 2 | 27 Jan 2021 | Wednesday | National Heroes Day |
| 3 | 26 Feb 2021 | Friday | Ash Wednesday |
| 4 | 10 Apr 2021 | Saturday | Good Friday |
| 5 | 13 Apr 2021 | Tuesday | Easter Monday |
| 6 | 18 May 2021 | Tuesday | Discovery Day |
| 7 | 15 Jun 2021 | Tuesday | Queen's Birthday |
| 8 | 06 Jul 2021 | Tuesday | Constitution Day |
| 9 | 06 Aug 2021 | Friday | Jamaica's Independence Day |
| 10 | 09 Nov 2021 | Tuesday | Remembrance Day |
| 11 | 25 Dec 2021 | Saturday | Christmas Day |
| 12 | 28 Dec 2021 | Tuesday | Boxing Day Observed |